Göbekli Tepe (Turkish: [ɟœbecˈli teˈpe], "Potbelly Hill"; known as Girê Mirazan or Xirabreşkê in Kurdish) is a Neolithic archaeological site in the Southeastern Anatolia Region of Turkey. Dated to the Pre-Pottery Neolithic, between c. 9500 and 8000 BCE, the site comprises a number of large circular structures supported by massive stone pillars – the world's oldest known megaliths. Many of these pillars are richly decorated with figurative anthropomorphic details, clothing, and reliefs of wild animals, providing archaeologists rare insights into prehistoric religion and the particular iconography of the period. The 15 m (50 ft)-high, 8 ha (20-acre) tell also includes many smaller buildings, quarries, and stone-cut cisterns from the Neolithic, as well as some traces of activity from later periods. The site was first used at the dawn of the Southwest Asian Neolithic period, which marked the appearance of the oldest permanent human settlements anywhere in the world. Prehistorians link...

A Type Ia supernova (read: "type one-A") is a type of supernova that occurs in binary systems (two stars orbiting one another) in which one of the stars is a white dwarf. The other star can be anything from a giant star to an even smaller white dwarf.Physically, carbon–oxygen white dwarfs with a low rate of rotation are limited to below 1.44 solar masses (M☉). Beyond this "critical mass", they reignite and in some cases trigger a supernova explosion; this critical mass is often referred to as the Chandrasekhar mass, but is marginally different from the absolute Chandrasekhar limit, where electron degeneracy pressure is unable to prevent catastrophic collapse. If a white dwarf gradually accretes mass from a binary companion, or merges with a second white dwarf, the general hypothesis is that a white dwarf's core will reach the ignition temperature for carbon fusion as it approaches the Chandrasekhar mass. Within a few seconds of initiation of nuclear fusion, a substantial fraction of the matter in the white dwarf undergoes a runaway reaction, releasing enough energy (1–2×10...

Skin aging is primarily due to alterations in the dermal extracellular matrix, especially a decrease in collagen I content, fragmentation of collagen fibrils, and accumulation of amorphous elastin material, also known as elastosis. Growth factors and ...

Pharmacology is a branch of medicine, biology, and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word pharmacon is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, functions, sources, synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. The two main areas of pharmacology are pharmacodynamics and pharmacokinetics...

Autodidacticism (also autodidactism) or self-education (also self-learning and self-teaching) is education without the guidance of masters (such as teachers and professors) or institutions (such as schools). Generally, autodidacts are individuals who choose the subject they will study, their studying material, and the studying rhythm and time. Autodidacts may or may not have formal education, and their study may be either a complement or an alternative to formal education. Many notable contributions have been made by autodidacts. Etymology The term has its roots in the Ancient Greek words αὐτός (autós, lit. 'self') and διδακτικός (...

A joke is a display of humour in which words are used within a specific and well-defined narrative structure to make people laugh and is usually not meant to be interpreted literally. It usually takes the form of a story, often with dialogue, and ends in a punch line, whereby the humorous element of the story is revealed; this can be done using a pun or other type of word play, irony or sarcasm, logical incompatibility, hyperbole, or other means. Linguist Robert Hetzron offers the definition: A joke is a short humorous piece of oral literature in which the funniness culminates in the final sentence, called the punchline… In fact, the main condition is that the tension should reach its highest level at the very end. No continuation relieving the tension should be added. As for its being "oral," it is true that jokes may appear printed, but when further transferred, there is no obligation to reproduce the text verbatim, as in the case of poetry. It is generally held that jokes benefit from brevity, containing...

A bill of rights, sometimes called a declaration of rights or a charter of rights, is a list of the most important rights to the citizens of a country. The purpose is to protect those rights against infringement from public officials and private citizens.Bills of rights may be entrenched or unentrenched. An entrenched bill of rights cannot be amended or repealed by a country's legislature through regular procedure, instead requiring a supermajority or referendum; often it is part of a country's constitution, and therefore subject to special procedures applicable to constitutional amendments. History The history of legal charters asserting certain rights for particular groups goes back to the Middle Ages and earlier. An example is the Magna Carta, an English legal charter agreed between the King and his barons in 1215. In the early modern period, there was renewed interest in the Magna Carta. English common law judge Sir Edward Coke revived the idea of rights based on citizenship by arguing that Englishmen had...

Coffee is a drink prepared from roasted coffee beans. Darkly colored, bitter, and slightly acidic, coffee has a stimulating effect on humans, primarily due to its caffeine content. It is the most popular hot drink in the world.Seeds of the Coffea plant's fruits are separated to produce unroasted green coffee beans. The beans are roasted and then ground into fine particles that are typically steeped in hot water before being filtered out, producing a cup of coffee. It is usually served hot, although chilled or iced coffee is common. Coffee can be prepared and presented in a variety of ways (e.g., espresso, French press, caffè latte, or already-brewed canned coffee). Sugar, sugar substitutes, milk, and cream are often used to mask the bitter taste or enhance the flavor. Though coffee is now a global commodity, it has a long history tied closely to food traditions around the Red Sea. The earliest credible evidence of coffee drinking in the form of the modern beverage appears in modern-day Yemen from the mid-15th century in Sufi shrines, where coffee seeds were first roasted and brewed in a manner similar to current methods...

Nauru ( nah-OO-roo or NOW-roo; Nauruan: Naoero), officially the Republic of Nauru (Nauruan: Repubrikin Naoero) and formerly known as Pleasant Island, is an island country and microstate in Oceania, in the Central Pacific. Its nearest neighbour is Banaba of Kiribati, about 300 km (190 mi) to the east. It further lies northwest of Tuvalu, 1,300 km (810 mi) northeast of Solomon Islands, east-northeast of Papua New Guinea, southeast of the Federated States of Micronesia and south of the Marshall Islands. With only a 21 km2 (8.1 sq mi) area, Nauru is the third-smallest country in the world behind Vatican City and Monaco, making it the smallest republic as well as the smallest island nation. Its population of about 10,000 is the world's second-smallest (not including colonies or overseas territories), after Vatican City. Settled by people from Micronesia circa 1000 BCE, Nauru was annexed and claimed as a colony by the German Empire in the...