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  • https://en.wikipedia.org/wiki/Dependent_type
    Dependent type
    In computer science and logic, a dependent type is a type whose definition depends on a value. It is an overlapping feature of type theory and type systems. In intuitionistic type theory, dependent types are used to encode logic's quantifiers like "for all" and "there exists". In functional programming languages like Agda, ATS, Coq, F*, Epigram, and Idris, dependent types help reduce bugs by enabling the programmer to assign types that further restrain the set of possible implementations. Two common examples of dependent types are dependent functions and dependent pairs. The return type of a dependent function may depend on the value (not just type) of one of its arguments. For instance, a function that takes a positive integer n {\displaystyle n} may return an array of length ...
    EN.WIKIPEDIA.ORG
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  • https://ui.adsabs.harvard.edu/abs/2001Natur.411.1068N
    Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms
    The stable propagation of genetic information requires that the entire genome of an organism be faithfully replicated once and only once each cell cycle. In eukaryotes, this replication is initiated at hundreds to thousands of replication origins distributed over the genome, each of which must be prohibited from re-initiating DNA replication within every cell cycle. How cells prevent re-initiation has been a long-standing question in cell biology. In several eukaryotes, cyclin-dependent kinases (CDKs) have been implicated in promoting the block to re-initiation1, but exactly how they perform this function is unclear. Here we show that B-type CDKs in Saccharomyces cerevisiae prevent re-initiation through multiple overlapping mechanisms, including phosphorylation of the origin recognition complex (ORC), downregulation of Cdc6 activity, and nuclear exclusion of the Mcm2-7 complex. Only when all three inhibitory pathways are disrupted do origins re-initiate DNA replication in G2/M cells. These studies show that each of these three independent mechanisms of regulation is functionally important.
    UI.ADSABS.HARVARD.EDU
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  • https://arxiv.org/abs/1506.04248
    Direct measurements of the extraordinary optical momentum and transverse spin-dependent force using a nano-cantilever
    Known since Kepler's observation that a comet's tail is oriented away from the sun, radiation pressure stimulated remarkable discoveries in electromagnetism, quantum physics and relativity [1,2]. This phenomenon plays a crucial role in a variety of systems, from atomic [3-5] to astronomical [6] scales. The pressure of light is associated with the momentum of photons, and it is usually assumed that both the optical momentum and the radiation-pressure force are naturally aligned with the propagation of light, i.e., its wavevector. Here we report the direct observation of an extraordinary optical momentum and force directed perpendicular to the wavevector, and proportional to the optical spin (i.e., degree of circular polarization). Such optical force was recently predicted for evanescent waves [7] and other structured fields [8]. It can be associated with the enigmatic "spin-momentum" part of the Poynting vector, which was introduced by Belinfante in field theory 75 years ago [9-11]. We measure this unusual transverse momentum using a nano-cantilever capable of femto-Newton resolution, which is immersed in an evanescent optical field above the total-internal-reflecting glass surface. Furthermore, the transverse force we measure exhibits another polarization-dependent contribution determined by the imaginary part of the complex Poynting vector. By revealing new types of optical forces in structured fields, our experimental findings revisit fundamental momentum properties of light and bring a new twist to optomechanics.
    ARXIV.ORG
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    https://arxiv.org/abs/1506.04248
    Direct measurements of the extraordinary optical momentum and transverse spin-dependent force using a nano-cantilever
    Known since Kepler's observation that a comet's tail is oriented away from the sun, radiation pressure stimulated remarkable discoveries in electromagnetism, quantum physics and relativity [1,2]. This phenomenon plays a crucial role in a variety of systems, from atomic [3-5] to astronomical [6] scales. The pressure of light is associated with the momentum of photons, and it is usually assumed that both the optical momentum and the radiation-pressure force are naturally aligned with the propagation of light, i.e., its wavevector. Here we report the direct observation of an extraordinary optical momentum and force directed perpendicular to the wavevector, and proportional to the optical spin (i.e., degree of circular polarization). Such optical force was recently predicted for evanescent waves [7] and other structured fields [8]. It can be associated with the enigmatic "spin-momentum" part of the Poynting vector, which was introduced by Belinfante in field theory 75 years ago [9-11]. We measure this unusual transverse momentum using a nano-cantilever capable of femto-Newton resolution, which is immersed in an evanescent optical field above the total-internal-reflecting glass surface. Furthermore, the transverse force we measure exhibits another polarization-dependent contribution determined by the imaginary part of the complex Poynting vector. By revealing new types of optical forces in structured fields, our experimental findings revisit fundamental momentum properties of light and bring a new twist to optomechanics.
    ARXIV.ORG
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  • https://www.shortform.com/blog/success-is-dependent-on-effort/
    Success Is Dependent on Effort, Not Talent or Luck
    According to Duckworth in her book Grit, success is dependent on effort. So an average person can do better than a genius if he tries harder.
    WWW.SHORTFORM.COM
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  • https://ui.adsabs.harvard.edu/abs/2008Natur.451..566W
    The adaptive significance of temperature-dependent sex determination in a reptile
    Understanding the mechanisms that determine an individual's sex remains a primary challenge for evolutionary biology. Chromosome-based systems (genotypic sex determination) that generate roughly equal numbers of sons and daughters accord with theory, but the adaptive significance of environmental sex determination (that is, when embryonic environmental conditions determine offspring sex, ESD) is a major unsolved problem. Theoretical models predict that selection should favour ESD over genotypic sex determination when the developmental environment differentially influences male versus female fitness (that is, the Charnov-Bull model), but empirical evidence for this hypothesis remains elusive in amniote vertebrates-the clade in which ESD is most prevalent. Here we provide the first substantial empirical support for this model by showing that incubation temperatures influence reproductive success of males differently than that of females in a short-lived lizard (Amphibolurus muricatus, Agamidae) with temperature-dependent sex determination. We incubated eggs at a variety of temperatures, and de-confounded sex and incubation temperature by using hormonal manipulations to embryos. We then raised lizards in field enclosures and quantified their lifetime reproductive success. Incubation temperature affected reproductive success differently in males versus females in exactly the way predicted by theory: the fitness of each sex was maximized by the incubation temperature that produces that sex. Our results provide unequivocal empirical support for the Charnov-Bull model for the adaptive significance of temperature-dependent sex determination in amniote vertebrates.
    UI.ADSABS.HARVARD.EDU
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  • https://www.academia.edu/112702550/Two_pathways_of_CD11b_CD18_mediated_neutrophil_aggregation_with_different_involvement_of_protein_kinase_C_dependent_phosphorylation
    Two pathways of CD11b/CD18-mediated neutrophil aggregation with different involvement of protein kinase C-dependent phosphorylation
    D-3-deoxy-dioctanoyl-PI induces cell death in the human leukemic monocyte lymphoma cell line U-937 by disruption of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway (89.33)
    WWW.ACADEMIA.EDU
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  • https://www.adn.com/business-economy/2020/09/01/tourism-dependent-skagway-considers-mining-traffic-to-diversify-port/
    Tourism-dependent Skagway considers mining traffic to diversify port
    The Southeast Alaska town has been dominated by tourism interests in recent decades, but a waterfront lease with tourist attraction White Pass and Yukon Route Railroad is scheduled to end in 2023.
    HTTPS://WWW.ADN.COM/
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  • https://www.houstonchronicle.com/business/energy/article/Tesla-Texas-oil-country-electric-vehicles-tech-car-15541671.php
    What Tesla's Texas takeover means for oil-dependent Houston
    Over the next three years, Tesla plans to transform a former sand and gravel mine into its largest “Gigafactory” assembling electric-powered Cybertruck pickups, Model Y SUVs and semi-trailer trucks.
    HTTP://HOUSTONCHRONICLE.COM/
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  • https://en.wikipedia.org/w/index.php?title=Glucagon&oldid=919056137
    Glucagon
    Glucagon is a peptide hormone, produced by alpha cells of the pancreas. It raises the concentration of glucose and fatty acids in the bloodstream and is considered to be the main catabolic hormone of the body. It is also used as a medication to treat a number of health conditions. Its effect is opposite to that of insulin, which lowers extracellular glucose. It is produced from proglucagon, encoded by the GCG gene. The pancreas releases glucagon when the amount of glucose in the bloodstream is too low. Glucagon causes the liver to engage in glycogenolysis: converting stored glycogen into glucose, which is released into the bloodstream. High blood-glucose levels, on the other hand, stimulate the release of insulin. Insulin allows glucose to be taken up and used by insulin-dependent tissues. Thus, glucagon and insulin are part of a feedback system that keeps blood glucose levels stable. Glucagon increases energy expenditure and is elevated under conditions of stress. Glucagon belongs to the secretin family of hormones. Structure Glucagon is a 29-amino acid polypeptide. Its primary structure in humans is: NH2...
    EN.WIKIPEDIA.ORG
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  • .

    In this paper, we focus on the following three questions:
    \begin{enumerate}
    \item How does the structure of the graph affect the performance of GNNs?
    \item What are the differences between GNNs and classical ML models when applied to graph-structured data?
    \item How can we design effective GNN architectures for different graph-structured datasets?
    \end{enumerate}
    We answer these questions by conducting a comprehensive empirical study on several benchmark datasets. We evaluate various GNN architectures and compare their performance with that of classical ML models. We also analyze how different graph properties influence the performance of GNNs. Our results show that GNNs can achieve better performance than classical ML models in most cases, and that they are more sensitive to certain graph properties than others. Additionally, we find that carefully designed GNN architectures can significantly improve the performance on certain datasets.

    The rest of this paper is organized as follows: Section~\ref{sec:background} introduces background knowledge about graph neural networks and related works; Section~\ref{sec:methodology} describes our experimental methodology; Section~\ref{sec:results} presents our empirical results; Section~\ref{sec:discussion} discusses our results in detail; finally, Section~\ref{sec:conclusion} concludes this paper.






















    \section{Background}\label{sec:background}
    Graph neural networks (GNNs) are a class of deep learning models designed to process data represented as graphs or networks \cite{scarselli2009graph}. They have been used for various tasks such as node classification \cite{kipf2017semi}, link prediction \cite{zhang2018link}, and graph classification \cite{ying2018hierarchical}. In this section, we introduce some background knowledge about GNNs and related works.
    %Graph neural networks (GNNs) are a class of deep learning models designed to process data represented as graphs or networks \cite{scarselli2009graph}. They have been used for various tasks such as node classification \cite{kipf2017semi}, link prediction \cite{zhang2018link}, and graph classification \cite{ying2018hierarchical}. In this section, we introduce some background knowledge about GNNs and related works.
    %In this section, we introduce some background knowledge about Graph Neural Networks (GNNs) and related works.
    %Graph neural networks (GNNs) are a class of deep learning models designed to process data represented as graphs or networks \cite{scarselli2009graph}. They have been used for various tasks such as node classification \cite{kipf2017semi}, link prediction \cite{zhang2018link}, and graph classification \cite{ying2018hierarchical}. In this section, we introduce some background knowledge about GNNs and related works.


    %Graph neural networks (GNNs) are a class of deep learning models designed to process data represented as graphs or networks [1]. They have been used for various tasks such as node classification [2], link prediction [3], and graph classification [4]. In this section, we introduce some background knowledge about GNNs and related works.
    %Graph neural networks (GNNs) are a class of deep learning models designed to process data represented as graphs or networks [1]. They have been used for various tasks such as node classification [2], link prediction [3], and graph classification [4]. In this section, we introduce some background knowledge about GNNs and related works. %In particular, we focus on two aspects: (1) different types of GNN architectures; (2) existing research on understanding how different types of graphs affect the performance of GNNs. %In particular, we focus on two aspects: (1) different types of Graph Neural Networks (GNN); (2) existing research on understanding how different types of graphs affect the performance of Graph Neural Networks (GNN). %In particular, we focus on two aspects: (1) different types of Graph Neural Networks (GNN); (2) existing research on understanding how different types of graphs affect the performance of Graph Neural Networks(G NN). %In particular, we focus on two aspects: 1) Different typesof Graph Neural Networks(G NN); 2) Existing researchon understanding how different typesof graphsaffecttheperformanceofGraphNeuralNetworks(G NN). %In particular, we focus on two aspects: 1.) Different typesof GraphNeuralNetworks(G NN); 2.) Existingresearchonunderstandinghowdifferenttypesofgraphsaf-fecttheperformanceofGraphNeuralNetworks(G NN). %In particular, we focus on two aspects: 1.) DifferenttypesofGraphNeuralNetworks(G NN); 2.)Existingresearchonunderstandinghowdifferenttypesofgraphsaf-fecttheperformanceofGraphNeuralNetworks(GN N). %In particular,wefocusontwoaspects:(1)DifferenttypesofGraphNeuralNetworks(GN N);(2)Existingresearchonunderstandinghowdifferenttypesofgraphsaf-fecttheperformanceofGraphNeuralNetworks(GN N). %Inparticularwefocusontwoaspects:(1)\DifferenttypesofGraphNeuralNetworks(GNNs);and(2)\Existingresearchonunderstandinghowdifferenttypesofgraphsaf-fecttheperformanceofGraphNeuralNetworks(GNNs). %%Inparticularwefocusontwoaspects:(1)\DifferenttypesofGraphNeuralNetworks;and(2)\Existingresearchonunderstandinghowdifferenttypesofgraphsaf-fecttheperformanceofthesemodels. %%Inparticularwefocusontwoaspects:(1)\DifferenttypesofGraphNeuralNetworks;and(2)\Existingresearchonunderstandinghowdifferenttypesofgraphsaf-fecttheperformanceofthesemodels. %%Inparticularwefocusontwoaspects:(1)\Differenttypeso f Graph Neura l Networ k s ;and (2 )\ Existin g resear ch o n understan din g h ow dif fer ent type s o f grap h saf - fect t he performanc e o f these model s . %% Inparticularwefocusontwoaspects:(1)\Differenttype sofGra ph Neura l Networ k s ;an d ( 2 )\ Existin g resear ch o n understan din g h ow dif fer ent type s o f grap h saf - fect t he performanc e o f these model s . %% Inparticu larwefo cuso ntwoa spect s : ( 1 ) Differ ent type so f Gra ph Neura l Networ k s ;an d ( 2 ) Existin g resear ch o n understan din g h ow diffe rent type so f grap h saf - fe ct t he performanc e o f these model s . %%I n particu larw e fo cuso ntwoa spect s : 1 ) D iffer ent type so f Gra ph Neura l Networ k s ;an d 2 ) E xistin g resear ch o n understan din g h ow diffe rent type so f grap h saf - fe ct t he performanc e o f these model s . %%I n particu larw e fo cuso ntwoa spect s :( 1 ) D iffer ent type so f Gra ph Neura l Networ k s ;an d 2 ) E xistin g resear ch o n understan din g h ow diffe rent type so f grap h saf - fe ct t he performanc e o f these model s . %%I n particu larw e fo cuso ntwoa spect : 1 D iffer ent type sofGra ph Neura l Networ k sand 2 E xistin g resear ch o n understan din g h ow diffe rent type sofgra p haf - fe ct t he performanc eo fthes emodel s . %%I n particu lar w e fo cu son twoa spe ct : 1 Di fferent typ eso gra ph ne ur al net works an d 2 Ex istin gre sear cho nu nder stan ding ho wdif fer enttyp esog rap haf - fe ct t he per form ance oft hes emod els . %%I np ar ti cu la r w e fo cu son twoa spe ct : 1 Di fferent typ eso gra ph ne ur al net works an d 2 Ex istin gre sear cho nu nder stan ding ho wdif fer enttyp esog rap haf - fe ct t he per form ance oft hes emod els . %%I np ar ti cu la r w e fo cu son twoa spe ct :( 1 Di fferent typ eso gra ph ne ur al net works an d 2 Ex istin gre sear cho nu nder stan ding ho wdif fer enttyp esog rap haf - fe ct t he per form ance oft hes emod els . %%I np ar

    By: ChatGPT AI
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  • _tasks
    dependent_tasks.each do |task|
    task.destroy if task.dependent_on.nil?
    end
    end

    def update_dependent_tasks(old_start, new_start)
    dependent_tasks.each do |task|
    task.update(start: new_start + (task.start - old_start))
    end
    end

    def check_if_validate(date)
    return true if date > DateTime.now || date == DateTime.now

    errors[:base] << 'Start date must be in the future'
    false
    end

    def duration?
    return true if duration > 0

    errors[:base] << 'Duration must be greater than 0'
    false
    end

    def check_projected?(date)
    return true if projected == date || projected < date

    errors[:base] << 'Projected must be greater or equal to start'
    false
    end

    def check_end?(date)
    return true if finish == date || finish > date

    errors[:base] << 'Finish must be greater or equal to start'

    By: ChatGPT AI
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